Julien Zuber, France

Dr Julien Zuber graduated from Necker’s Medical School, Paris. He did a PhD in Immunology at Pasteur Institute, where he established a link between autoimmune enteropathy/nephropathy and FOXP3+ regulatory T cell deficiency. He was appointed Assistant Professor of nephrology in 2009. He subsequently developed expertise in atypical hemolytic uremic syndrome and C3 glomerulopathies, associated with complement alternative pathway dysregulation. He contributed to the developement of highly-targeted therapies based on complement blockade. In 2012, he moved to New York as Fulbright fellow and joined Dr Megan Sykes’ lab at the Columbia Center for Translational Immunology. His work investigated the relationship between hematopoietic chimerism and the two-way alloimmune response in intestinal transplant recipients, using innovative tools to track alloreactive T cells. Upon his return to France, he was appointed Associate Professor of nephrology in 2015 and then full Professor of clinical immunology in 2017, sharing his time between the department of kidney transplantation, at Necker hospital, and the institute of genetics and immunology IMAGINE. He initially joined Marina Cavazzana’s lab in 2016. He was subsequently appointed Theme leader by the IMAGINE's scientific advisory board, and has been running a research team since 2017. His research is exploring several fields of investigations, including CAR-engineering of human regulatory T cells, mixed chimerism-based tolerance, as well as strategies to mitigate the impact of anti-HLA sensitization in transplantation and during pregnancy.